Multisystem inflammatory syndrome associated with COVID-19 in adult: the case report

The multisystem inflammatory syndrome associated with COVID-19 coronavirus infection was first described in April-May 2020, mainly among children who had an acute infectious disease. Soon there were reports of the development of MIS in adults (MIS-A). More than 200 cases of MVS in adults have been described and systematized in the world, while in Russia there is no separate registration of MVS, a single description of MVS is given in the literature. Material and methods. We presented Case report of MIS-A in a 21-year-old woman, accompanied by persistent fever, multiple organ failure syndrome, is presented. The stages of diagnosis and treatment of MIS-A. Result and discussion. A positive effect was achieved during therapy with corticosteroids and intravenous immunoglobulin. MIS-A is a rare life-threatening complication of a COVID-19 that requires emergency therapy with the inclusion of corticosteroids and intravenous immunoglobulin in an adequate dose. The given example will be interesting for general practitioners, infectious disease specialists and therapists.Copyright © 2023 The authors.

Multisystem inflammatory syndrome associated with COVID-19 in adult: the case report.

The multisystem inflammatory syndrome associated with COVID-19 coronavirus infection was first described in April-May 2020, mainly among children who had an acute infectious disease. Soon there were reports of the development of MIS in adults (MIS-A). More than 200 cases of MVS in adults have been described and systematized in the world, while in Russia there is no separate registration of MVS, a single description of MVS is given in the literature. Material and methods. We presented Case report of MIS-A in a 21-year-old woman, accompanied by persistent fever, multiple organ failure syndrome, is presented. The stages of diagnosis and treatment of MIS-A. Result and discussion. A positive effect was achieved during therapy with corticosteroids and intravenous immunoglobulin. MIS-A is a rare life-threatening complication of a COVID-19 that requires emergency therapy with the inclusion of corticosteroids and intravenous immunoglobulin in an adequate dose. The given example will be interesting for general practitioners, infectious disease specialists and therapists.Copyright © 2023 The authors.

Emergency short stay area improves access and flow in a rural hospital.

OBJECTIVES: Shoalhaven District Memorial Hospital is a rural (MM3) 150-bed hospital in Nowra, New South Wales, whose ED has evolved to a FACEM-led model of care (MOC). It has never had an emergency short stay area (ESSA). The objective of the present study was to pilot an ESSA and determine whether this MOC would increase the operational performance of the ED. METHODS: An ESSA was designed and delivered by emergency medicine medical, nursing and allied health practitioners. The study period was July-December 2021, with a seasonally matched retrospective cohort of records extracted for comparison (July-December 2020). Both took place within the context of the ongoing COVID-19 pandemic. The primary outcome measured was percentage of admitted patients meeting Emergency Treatment Performance (ETP). Secondary outcomes included discharge ETP, overall ED and inpatient length of stay (LOS), mortality and representation rates. RESULTS: The admission ETP for patients after the implementation of the ESSA significantly increased, from 13.9% to 31.6% (χ2 = 288, P < 0.001). Discharge ETP significantly declined. There was no effect improvement on overall ETP. There was no change to mortality or representation rates. Average admission LOS decreased. CONCLUSIONS: The introduction of the ESSA significantly improved the ETP of admitted patients. Ongoing refinement of the ESSA admission processes, as well as the lifting of certain COVID-19 restrictions, could show even greater improvements in this and other areas. Ongoing research in this field is necessary, as well as a more detailed cost-benefit analysis.

Effect of COVID-19 on cardiac electrophysiology practice: a systematic review of literature.

The authors conducted a systematic review on the effect of coronavirus disease 2019 on electrophysiology (EP) practice and procedure volume in various settings. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. PubMed/MEDLINE, Scopus, Web of Science, CINAHL, and Embase were examined with combinations of medical subject headings terms for identification of the relevant studies. After excluding duplicates, irrelevant, and ineligible studies, 23 studies were included for full qualitative analysis. The overall study-level volume reduction of EP procedures ranged from 8 to 96.7%. All studies reported an overall reduction in EP physiology procedures being carried out except one in Poland, which reported an overall increase in the total EP procedures carried out in 2020. This study still reported a decrease in EP procedure volume during the first lockdown phase. Procedural volume reduction was seen most commonly for cardiovascular implantable electronic device placement (20/23 studies, 86.9%), electrophysiology studies (11/23 studies, 47.8%), and ablations (9/23, 39.1% studies). The most common reason stated for the observed decline in EP procedures was the cancellation and postponement of nonurgent elective cases in the hospitals (15/23 studies, 65.2%). There has been an overall reduction in EP procedure volume across different centers. The impact of the decline in EP procedures will be seen only after the services resume to prepandemic levels, but an increase in-patient volume and procedure waiting time is expected. This review will provide insights into improving healthcare service delivery in times of unprecedented public health emergencies.

The characteristics of SARS-CoV-2-positive children in Australian hospitals: a PREDICT network study.

OBJECTIVES: To examine the clinical characteristics and short term outcomes for children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections who presented to Australian hospitals during 2020 and 2021. DESIGN, SETTING: Retrospective case review study in nineteen hospitals of the Paediatric Research in Emergency Departments International Collaborative (PREDICT) network from all Australian states and territories, including seven major paediatric tertiary centres and eight Victorian hospitals. PARTICIPANTS: SARS-CoV-2-positive people under 18 years of age who attended emergency departments or were admitted to hospital during 1 February 2020 - 31 December 2021. MAIN OUTCOME MEASURES: Epidemiological and clinical characteristics, by hospital care type (emergency department [ED] or inpatient care). RESULTS: A total of 1193 SARS-CoV-2-positive children and adolescents (527 girls, 44%) attended the participating hospitals (107 in 2020, 1086 in 2021). Their median age was 3.8 years (interquartile range [IQR], 0.8-11.4 years); 63 were Aboriginal or Torres Strait Islander people (5%). Other medical conditions were recorded for 293 children (25%), including asthma (86, 7%) and premature birth (68, 6%). Medical interventions were not required during 795 of 1181 ED presentations (67%); children were discharged directly home in 764 cases (65%) and admitted to hospital in 282 (24%; sixteen to intensive care units). The 384 admissions to hospital (including 102 direct admissions) of 341 children (25 infants under one month of age) included 23 to intensive care (6%); the median length of stay was three days (IQR, 1-9 days). Medical interventions were not required during 261 admissions (68%); 44 children received respiratory support (11%) and 21 COVID-19-specific treatments, including antiviral and biologic agents (5%). Being under three months of age (v one year to less than six years: odds ratio [OR], 2.6; 95% confidence interval [CI], 1.7-4.0) and pre-existing medical conditions (OR, 2.5; 95% CI, 1.9-3.2) were the major predictors of hospital admission. Two children died, including one without a known pre-existing medical condition. CONCLUSION: During 2020 and 2021, most SARS-CoV-2-positive children and adolescents who presented to participating hospitals could be managed as outpatients. Outcomes were generally good, including for those admitted to hospital.

Do Not Attempt Conversations Pre-Rehearsal: Teaching Medical Students to Have Dnacpr Conversations

Introduction The Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) form is widely adopted to document advanced care plans, including Do Not Attempt Resuscitation (DNACPR) decisions. Communication between clinicians and patients, or next of kin is required for completion. It is widely documented UK medical students have little exposure to these experiences, including being asked to leave whilst they are occurring. During the COVID19 pandemic, Foundation Year 1 (FY1) doctors led discussions with increased frequency and autonomy, with no documented concurrent training. We present a novel learning experience designed to aid these discussions. Students were timetabled to a 1.5 hour workshop, facilitated by a clinical teaching fellow. They were invited to complete ReSPECT form for a celebrity to familiarise themselves with the layout. They then considered a patient admission scenario in 3 different groups from the perspective of the patient, family and medical team, and used this to contemplate potential, future, emergency treatments. Subsequently a discussion surrounding CPR effectiveness, ways of communicating this, and legal advanced decision documents occurred. The session concludes with scrutinising example ReSPECT forms provided by the Resuscitation Council UK. Method Students' confidence levels were measured pre and post session using a Likhert scale questionnaire. Results 90 students attended workshops across 6 rotations. 80% students completed post - session questionnaires, of which 100% reported an increase in confidence with having a DNACPR/advanced care planning discussion compared to before the session. Conclusion DNACPR conversations can incite anxiety in any seniority of health care professionals. Medical educators need to adequately prepare medical students during their training in advanced care planning and DNACPR discussions. This can be done with simulated workshop experiences, reinforced with opportunistic or organised observational experience. Adequate preparation will lead to increased confidence in discussions, ultimately leading to better experiences for patients and their families.

Screening and intervention for intimate partner violence at trauma centers and emergency departments: an evidence-based systematic review from the Eastern Association for the Surgery of Trauma.

Background: Intimate partner violence (IPV) is a serious public health issue with a substantial burden on society. Screening and intervention practices vary widely and there are no standard guidelines. Our objective was to review research on current practices for IPV prevention in emergency departments and trauma centers in the USA and provide evidenced-based recommendations. Methods: An evidence-based systematic review of the literature was conducted to address screening and intervention for IPV in adult trauma and emergency department patients. The Grading of Recommendations, Assessment, Development and Evaluations methodology was used to determine the quality of evidence. Studies were included if they addressed our prespecified population, intervention, control, and outcomes questions. Case reports, editorials, and abstracts were excluded from review. Results: Seven studies met inclusion criteria. All seven were centered around screening for IPV; none addressed interventions when abuse was identified. Screening instruments varied across studies. Although it is unclear if one tool is more accurate than others, significantly more victims were identified when screening protocols were implemented compared with non-standardized approaches to identifying IPV victims. Conclusion: Overall, there were very limited data addressing the topic of IPV screening and intervention in emergency medical settings, and the quality of the evidence was low. With likely low risk and a significant potential benefit, we conditionally recommend implementation of a screening protocol to identify victims of IPV in adults treated in the emergency department and trauma centers. Although the purpose of screening would ultimately be to provide resources for victims, no studies that assessed distinct interventions met our inclusion criteria. Therefore, we cannot make specific recommendations related to IPV interventions. PROSPERO registration number: CRD42020219517.

Assessment of Endodontic Emergency Care in a COVID-19 Pandemic

Objective: This study compared the aerosol-generating and non-aerosol-generating endodontic emergency procedures' success and assessed the outcome of endodontic treatments initiated before a pandemic but could not be completed in the targeted time. Material(s) and Method(s): Emergency treatments were performed according to symptoms of teeth. Treatment success or failure was determined according to patients whether not re-referral with untimely pain. Short-term outcome and complications arising from teeth, which endodontic treatments were prolonged were also recorded. A chi-square test was used in the statistical analysis, and p<0.05 was considered significant. Result(s): The aerosol-generating procedure group's success rate was 86.2%, while it was 70.0% in the non-aerosol generating procedure group (p=0.050). The short-term survival rate of teeth was 83.7% in patients whose endodontic treatment had been prolonged. Conclusion(s): Considering the pros and cons, each emergency patient should be evaluated case-by-case. Copyright ©Meandros Medical and Dental Journal, Published by Galenos Publishing House.

Cough Audio Signal-Based Clinical Emergency Classification of Corona Variant Infected Patients Using Multiclass SVM

The variants of coronavirus both delta and omicron are much more contagious and affecting greater percentage of human population. In this research, an attempt is made to predict classification of clinical emergency treatment of corona variant infected patients using their recorded cough sound file. Cough audio signal features such as zero crossing and mel-frequency cepstral coefficients (MFCC), chromo gram (chroma_stft), spectral centroid, spectral roll off, spectral-bandwidth are to be extracted and stored along with patient ID, date, and timings. Digital signal processing of recorded cough audio file obtained needs to be cleaned and pre-processed and normalized to get a training dataset in order to build intelligent ML model using multiclass classifier SVM for predicting the class labels with maximum accuracy. The model proposed in this research paper helps to systematically plan and handle emergency treatment of the patients by classifying their severity based on the cough audio signal using SVM. The built model predicts and classifies the emergency treatment level as low, medium, and high with 96% accuracy. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

[Use of emergency services for suicide attempts during the SARS-CoV-2 pandemic-a prevalence study]. / Inanspruchnahme des Rettungsdiensts bei Suizidversuchen im Verlauf der SARS-CoV-2-Pandemie.

Background: The pandemic has caused several changes in the emergency care system. The deployment figures in emergency medical services have shown atypical fluctuations. This has also been explained by changes in behavior and an increased sense of stress among the population. Existing research provides hints for the increased incidence of mental health symptoms in emergency care during ongoing pandemics. Objective: In this context, this paper examines the occurrence of emergency medical services calls related to the keyword suicide in relation to total calls. Methods: This is a retrospective cross-sectional study based on routine documentation from a fire and rescue dispatch center with descriptive and exploratory data analyses. The data are divided by settlement-structural county types and compared with incidences and pandemic phases. Results: Phase 1 and 2a show a decrease in the number of dispatches during the pandemic. In addition, there is a shift in the number of dispatch cases with a context of suicide by structure types in phase 3. A decreased dispatch rate in the sparsely populated rural county is offset by an increase in the metropolitan area. Changes made to the control center system resulted in an increase in the number of dispatch cases in the context of suicide. Conclusion: Continuous mental health surveillance, including data collected by emergency medical services, can provide valuable insight. The study also highlights the need for standardization of emergency dispatch center data.

Einsatz von OTC-Arzneimitteln bei SARS-CoV-2-Infektionen

Published studies from 2021 found that acetylsalicylic acid (ASA) can improve the course of disease in hospitalized covid-19 patients and that these patients were less likely to suffer from covid-19 infection. Based on this, a retrospective data collection of 866 covid-19 patients who received treatment with OTC drugs and their disease course was collected using a survey (2021/2022). The group of patients receiving treatment with ASA was significantly older and more severely baseline ill than the comparison groups of patients treated with either ibuprofen, acetaminophen, or no OTC drugs. Although the SARS-CoV-2 patients with ASA were older and more severely predisposed, the course of treatment was comparable to younger and more mildly predisposed patients. Symptoms such as limb pain and chills, for example, were documented more frequently in the subgroup (treatment with ibuprofen and acetaminophen, respectively). Likewise, purely from the relative values, patients with ASA treatment were mostly better off when it came to the accumulation of outpatient treatments, emergency treatments, hospitalizations, and specialist referrals. A significant difference could be shown regarding outpatient treatments and emergency treatments of patients with ASA treatment compared with patients treated with acetaminophen. The results are indications that ASA may promote a milder course of disease in patients suffering from SARS-CoV-2 infection. Copyright © 2022 Georg Thieme Verlag. All rights reserved.

Direct streaming of acute surgical patients to an advanced nurse practitioner-led service: A prospective audit of a pilot service to improve patient flow

Aims: The ongoing uncertaintyofThe COVID-19 pandemic and recovery to re-establish elective services presents a major challenge to The NHS. Patient flow and bed capacity is now a priority for acute hospitals. We have implemented a new service model aimed at improving patient flow from A&E, where acute surgical patients are triaged and referred directly to The Advanced Nurse Practitioner (ANp) team for assessment and management. A criterion based on The presenting complaint and clinical observations was developed to identify suitable patients. The utilisation of this service was audited for its safety and impact on The Emergency General Surgical provision. Method(s): The setting is a busy University Teaching Hospital with a diverse catchment population of 75,000. A prospective audit identified The number of patients utilising The new care pathway and details of any adverse events or delays in treatment identified. All patients presenting with a General Surgical condition were included. Result(s): Between August and December 2021, 361 patients were referred directly from A&E (81% within first 2 hours of presentation) to The surgical ANp team for assessment. of these, 85 (24%) were admitted for Emergency treatment and 276 (76%) were discharged The same day for either ambulatory or outpatient follow-up, or back to Primary Care. There were no adverse events identified during The audit period. Conclusion(s): Direct streaming of acute surgical patients within a defined criteria to an ANp-led service is safe and effective in helping to improve patient flow and experience within an acute care model.

Research progress of therapeutic antibodies against COVID-19

Antibody-based biological products have gradually become a new strategy for the treatment of infectious diseases. In the past few years, especially after the outbreak of the COVID-19 in 2019, researches on therapeutic SARS-CoV-2 antibodies have greatly developed. Researchers around the world have developed a series of antibody treatment programs with extremely high efficiency to fight against COVID-19. From the early days of the pandemic, therapeutic antibodies were only used for emergency treatment of clinically severe patients, now they can be used for both pre-exposure prophylaxis and post-infection treatment. We summarize the research progress of therapeutic antibodies for SARS-CoV-2, including convalescent plasma, animal antiserum, marketed mAbs, non-targeted therapeutic mAbs, and bispecific antibodies, etc. The limitations and future application prospects of the SARS-CoV-2 therapeutic mAbs are also discussed. Copyright © 2022, Chinese Journal of New Drugs Co. Ltd. All right reserved.

Decision-making changes for patients and medical personnel in the management of acute appendicitis during the COVID-19 pandemic.

BACKGROUND: Acute appendicitis is the most common cause of acute abdomen. During the pandemic, to contain the spread of COVID-19, there were some integral changes in the medical processes based on the pandemic prevention policy, especially regarding emergency surgery. This study was conducted to investigate whether this pandemic also impacted the decision-making for both patients and medical personnel along with the treatment outcomes. METHODS: Patients of age 18 years or older who were diagnosed clinically and radiologically with acute appendicitis between Jan 1, 2017, and Dec 31, 202,0 were reviewed. The data of 1991 cases were collected and used for this study. Two groups were formed, one group before and the other group after the outbreak. The gathered data included gender, age, appendiceal fecalith, outcomes of treatment, and long-term outcomes of non-operation (8 months follow-up). We also collected details of surgical cases from the above two groups. This data also included age, gender, appendiceal fecalith, fever, jaundice, length of onset before presenting to an emergency department (ED), anesthesia, surgery, white cell count, pathology, complications, and length of stay. We compared the above data respectively and analyzed the differences. RESULTS: Compared to the period before the outbreak, patient visits for acute appendicitis remarkably dropped (19.8%), but surgical cases showed no change (dropped by roughly 5%). There were significant differences (P < 0.05) in failure of non-operation(after the pandemic 8.31% vs. before pandemic 3.22%), interval appendectomy(after pandemic 6.29% vs. before pandemic 12.84%), recurrence(after pandemic 23.27% vs. before pandemic 14.46%), and outcomes of recurrence. There was a significant difference (P < 0.05) in anesthesia method, surgery way, and complications( before pandemic 4.15% vs. after pandemic9.89% P < 0.05) in patients who underwent the surgery. There was no statistical difference (P > 0.05) concerning age, gender, fever, jaundice, appendiceal fecalith, white cell count, and length of onset before presenting to the ED. CONCLUSION: The current pandemic prevention policy is very effective, but some decision-making processes of doctor-patient have changed in the context of COVID-19 pandemic, that further influenced some treatment outcomes and might lead to a potential economic burden. It is essential to address the undue concern of everyone and optimize the treatment process.

CLINICAL RESPONSE PREDICTORS of TOCILIZUMAB THERAPY in PATIENTS with SEVERE COVID-19

Background: Aberrant immune response is hallmark of severe COVID-19, irrespectively from viral replication. Immunomodulatory therapies such as interleukin-6 (IL-6) receptor inhibitors were proven to be benefcial in reducing in-hospital mor-tality1. Yet, it remains unclear which patients can beneft most from such therapy. Objectives: To identify predictors of clinical response to tocilizumab (TCZ) added to dexamethasone in patients hospitalized with severe COVID-19. Methods: We prospectively assessed clinical and laboratory details of 120 patients hospitalized due to severe COVID-19 treated with TCZ (two doses of 8 mg/kg 24h apart) in our ward between 1st Feb 2021 and 31st Dec 2021. Severe COVID-19 was defned as SpO2 <94% on room air with ground glass opacities in chest computed tomography (CT). Clinical response was defned as respiratory improvement on day 5 after TCZ infusion compared to day of treatment initiation, no further deterioration and survival. Decision of adding TCZ to dexamethasone as emergency therapy was made collectively by rheumatologists experienced in COVID-19 treatment. Laboratory and clinical parameters from hospital admission day and from TCZ institution day were analyzed. Statistical analysis was conducted with PQStat v.1.8.2 and predictors were identifed in univariate logistic regression. Results: We identifed 86 (71.7%) clinical responders and 34 (28.3%) non-re-sponders. 20 (58.8%) of the second group needed ICU admission, 18 (52.9%) died on ICU and 2 patients (5.9%) died on the ward. Responders were signif-cantly younger (mean age 56.1 vs. 63.5 years, p=0.006), had lesser comorbidity burden (median Charleson Comorbidity Index 2 vs. 3, p=0.005), lower median lung involvement (50 vs. 70%, p<0.001), higher median baseline PaO2/FiO2 index (203 vs. 106, p<0.001) and less of them needed high-fow oxygen therapy on TCZ initiation day (12.7% vs 32.4%, p=0.025). Identifed predictors of clinical response are shown in Table 1. Conclusion: Administration of TCZ early in severe disease, with moderate IL-6 concentration and low organ damage indices is most benefcial in patients with severe COVID-19, especially in younger patients without respiratory and cardiac comorbidities.

Emergency care management of the sick child-observation and assessment

Background and objectives: The Royal College of Paediatrics and Child Health's (RCPCH) "Facing the Future: Standards for children in Emergency Care Settings" recommend full integration of pediatric emergency care, facilitating correct and timely assessment and treatment of children in the emergency care setting. This study focused on the "Management of the sick or injured child": "All children attending emergency care settings are visually assessed by a doctor or nurse immediately upon arrival with clinical assessment undertaken within 15 minutes to determine priority category, supplemented by a pain score and a full record of vital signs." The primary aim was to determine the baseline compliance rates against the national standards of pediatric care. This study is timely, with current increased waiting times and delays to emergency treatment causing UK government concern and implementation of emergency action due to patient safety concerns during the current Coronavirus-19 pandemic. Methods: In all, 61 pediatric patients admitted from May to June 2021 were reviewed using data from a NHS Trust Hospital Accident and Emergency system against the national standards. Children up to the age of 16 were included in the study. Clinical assessment times, vital sign completion, and staff review were all data collected and analyzed to determine the baseline. Results: National standards for assessment and observation were not met over the 2months analyzed. No children were immediately assessed by a doctor or a nurse upon arrival in either month. The average time to undertake a clinical assessment in June was 28 min, almost double the recommended time;65% of children were clinically assessed within 15 min in May and 23% in June. The recommendation for clinical assessment to be supplemented, by a full set of vital signs and a pain score, was achieved in 32% and 10% of patients in May and June, respectively. Discussions with the multidisciplinary team suggested a lack of infrastructure, staff shortages, and lack of training causing shortfall in meeting standards. Conclusion: These data support hospital departments to implement quality improvement schemes to enhance pediatric treatment and safe patient movement through emergency departments.

Emergency department: COVID-19 crisis and organizational aspects

Emergency departments are on the front line in the management of COVID-19 cases, from screening to the initial management of the most severe cases. The clinical presentation of COVID-19 range from non-specific symptoms to adult acute respiratory distress syndrome (ARDS). Diagnosis is based on PCR from a nasopharyngeal swab and emergency treatment rely on oxygen therapy. Patient’s orientation (home, hospitalization, admission in intensive care unit) is a central aspect of emergency management. The shift from a strategy of systematic recognition of potential cases to the one of epidemic mitigation required hospital emergency medicine services to implement crisis management measures, to guarantee admission and hospitalization capacity.

RELATIONSHIP KNOWLEDGE TRANSMISSION OF COVID 19 AND FEAR OF DENTAL CARE DURING PANDEMIC- A POPULATION BASED SURVEY

Introduction :Dental phobia is linked to avoiding dental checkups as well as poor oral health outcomes. During COVID-19, it is critical to analyse the distribution of dental fear and preference for emergency dental treatment across the adult population. As a result, the goal of this study was to assess dental phobia and emergency dental therapy among COVID-19 quarantined general population. Therefore the aim of this study is to determine the relationship between transmission and knowledge of COVID-19 and fear for dental treatment during pandemic among the general population. Materials and Methods: Online questionnaire using Google forms distributed through social media .The level of knowledge about coronavirus transmission was measured using a questionnaire consisting of knowledge and level of fear questions . 100 participants were the sample size. The questionnaire gives the responses and anxiety categories for dental care during pandemic. Results :100 respondents came from media users. Respondents who experienced "dental health problems" during the pandemic were 60%. The knowledge of respondents about the transmission of the COVID-19 virus in dental care was 80% and the knowledge of the fear of caring during the pandemic period was 50.67% afraid. Statistical analysis showed a significant relationship between knowledge about transmission of the COVID-19 virus and fear of dental care (p<0.005). Conclusion: The results obtained have a significant relationship between knowledge about transmission and fear for dental care during the COVID-19 pandemic among the general population.